Computer Methods and Programs in Biomedicine, v. 205. Abstract: The aim of this study is to present a new methodology to explore a field of research and exercise this technique to find good mathematical models to solve the problem of territorial alignment applied to health services. For this purpose we show a methodology that combines three methods of analysis: social network analysis, longitudinal analysis, and mapping change analysis. In this paper, we applied the mapping change method, originally used in large networks, to small and medium ones, and used the Tabu search scheme instead of simulated annealing. Finally, to highlight the significant changes over time of keywords networks, an alluvial diagram is used to show the significance clusterings through the subperiods studied. The work reports on the most relevant authors on the subject and the most widely used mathematical models applied to solve the problem.